Buy Flibanserin HCL powder (147359-76-0) hplc≥98% – Wisepowder

Buy Flibanserin HCL powder (147359-76-0) hplc≥98% – Wisepowder https://www.wisepowder.com/product-details/147359-76-0/ Base Information Name Flibanserin Hydrochloride powder CAS 147359-76-0 Purity 98% Chemical name Flibanserin Hydrochloride Synonyms BIMT 17 Hydrochloride; BIMT 17BS Hydrochloride; 1-(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazol-2(3H)-one Hydrochloride Molecular Formula C20H21F3N4O.ClH Molecular Weight 426.863 Melting Point…

Buy Flibanserin HCL powder (147359-76-0) hplc≥98% - Wisepowder

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Buy Flibanserin HCL powder (147359-76-0) hplc≥98% – Wisepowder

https://www.wisepowder.com/product-details/147359-76-0/

Base Information
Name Flibanserin Hydrochloride powder
CAS 147359-76-0
Purity 98%
Chemical name Flibanserin Hydrochloride
Synonyms BIMT 17 Hydrochloride; BIMT 17BS Hydrochloride; 1-(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazol-2(3H)-one Hydrochloride
Molecular Formula C20H21F3N4O.ClH
Molecular Weight 426.863
Melting Point >225°C
InChI Key XGAGFLQFMFCIHZ-UHFFFAOYSA-N
Form Solid
Appearance White to Pale Yellow
Half Life ≈11 hours
Solubility DMSO (Slightly), Methanol (Slightly)
Storage Condition Room Temperature
Application Flibanserin Hydrochloride is a 5-HT1A agonist and 5-HT2A antagonist that is developed for the treatment of hypoactive sexual desire disorder in women (1,2).
Testing Document Available

03 Flibanserin Hydrochloride powder General Description
Flibansetrin Hydrochloride has high affinity for serotonin receptors in the brain: it acts as an agonist on 5-HT1A and an antagonist on 5-HT2A. In vivo, flibanserin Hydrochloride binds equally to 5-HT1A and 5-HT2A receptors. However, under higher levels of brain 5-HT (i.e., under stress), flibanserin Hydrochloride may occupy 5-HT2A receptors in higher proportion than 5-HT(1A) receptors. It may also moderately antagonize D4 (dopamine) receptors and 5-HT2B and 5-HTB2C. Its action on neurotransmitter receptors may contribute to reduction in serotonin levels and increase in dopamine and norepinephrine levels, all of which may play part in reward processing. Flibanserin Hydrochloride is sold under the trade name Addyi and indicated for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) as characterized by low sexual desire that causes marked distress or interpersonal difficulty

04 Flibanserin Hydrochloride powder History
Flibanserin is the first drug to be approved for hypoactive sexual desire disorder (HSDD) in premenopausal women by the FDA in August 2015. It was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of efficacy in trials and was further developed as a hypoactive sexual disorder drug by Sprout Pharmaceuticals.

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